Curriculum Vitae

 

Education


MBA: Medical Industry Leadership Focus                                      August 2012

Carlson School of Management, University of Minnesota, Minneapolis, MN

 

Ph.D.: Biomedical Engineering                                                     May 2006

Tulane University, New Orleans, LA

 

M.Engr: Biomedical Engineering                                                  May 2005

Tulane University, New Orleans, LA

 

B.S.: Biomedical Engineering, EE Emphasis                                   May 1999

Louisiana Tech University, Ruston, LA

 

Professional Experience


RESPICARDIA     Minnetonka, MN                                          March 2010 – Present

Scientist, Research and Development

 

  • Collaborated with global field team and developed software tools to optimize patient therapy and outcomes
  • Partnered with Scientific Advisory Board to assess and investigate unmet research and clinical needs
  • Designed and implemented dashboards and automated processes to support prioritization of incoming data and ensure timely return of results, timely payment to clinical sites, and screening metrics resulting in headcount savings
  • Developed automated tools for data collection and led verification efforts to ensure the tools performed to specifications
  • Designed and implemented data collection, database, and analysis processes and systems to allow rapid and insightful analysis of incoming feasibility data to yield insights into optimizing therapy, regulatory reporting, remede® Pivotal Trial inclusion criteria and fundraising activities
  • Managed external core lab for remede® Pivotal Trial Endpoint Data
  • Developed data infrastructure to ensure transparency and integrity of remede® Pivotal Trial data for 14 of 27 primary and secondary endpoints
  • Participated in the data preparation and authorship of peer reviewed manuscripts
  • Ideation and Intellectual Property development

 

MEDTRONIC, Fridley Minnesota                                September 2005 – March 2010

Senior Scientist – High Power Leads Research

  • Planned investigations into strategic areas relating to next generation defibrillation leads and ICDs
  • Developed and leveraged partnership with internal customers and external KOLs to identify strategic areas of opportunity, create a roadmap to establish market superiority of ICD Leads, and align priorities
  • Designed and executed preclinical experiments for concept development and feasibility research relating to high-power defibrillation leads (LLV, ULV and DFT)
  • Developed tools for analysis of large datasets from de-identified Carelink data
  • Implemented biweekly intellectual property updates to stakeholders, regarding new submissions of interest, published by USPTO
  • Partnered with leadership to develop Professional Development Workshops on Innovation for technical contributors

Anatomy, Physiology and Imaging Group

  • Designed, and coordinated human research feasibility studies and directed data analysis
  • Designed and executed preclinical experiments to aid in concept development and feasibility research
  • Provided critical input to internal groups and design engineers in the form of design parameters and in vivo use conditions derived from imaging studies, computational field modeling, preclinical experiments, and other methodologies
  • Formed collaboration with Neuromodulation to adapt novel IP for next generation CRT leads resulting in four submitted patent applications (two issued patents)
  • Performed anatomical/device reconstructions using CT, MRI and calibrated biplane fluoroscopy image datasets for Test Development Engineers
  • Authored nine peer-reviewed internal publications; one selected as a distinguished poster presentation

 

Tulane University, New Orleans, LA                   September 2001 – February 2006

Research Assistant, Computational Cardiac Electrophysiology Group

Advisor: Dr. Natalia A. Trayanova

  • Planned and conducted hypotheses driven research studies
  • Author of three manuscripts and four poster publications in peer-reviewed journals

 

Univ. of Alabama Birmingham, Birmingham, AL         May 2000 – September 2001

Research Assistant, Cardiac Rhythm Management Laboratory

Co-Advisor: Dr. Richard A. Gray

  • Conducted optical mapping studies and data analysis
  • Designed and constructed devices as needed to conduct experimental studies

 

Publications


Dissertation:

Bourn DW, Cardiac Vulnerability and the Isoelectric Window, Tulane University, 2005.

 

Refereed Journal Publications:

 

Bourn DW, Maleckar MM, Rodriguez B, Trayanova NA. Mechanistic enquiry into the effect of pre-fibrillatory activity on the upper limit of vulnerability. Phil. Trans. of the R Soc., 2006;364:1333-1348

 

Bourn DW, Trayanova NA, Gray RA. Characterization of the relationship between pre-shock state and virtual electrode polarization-induced propagated graded response resulting in arrhythmia induction. Heart Rhythm J., 2006;3:583-595

 

Trayanova NA, Gray RA, Bourn DW, Eason JC, Virtual electrode induced positive and negative graded response:  New insights into fibrillation induction and defibrillation, J Cardiovasc Electrophysiol, 2003;14:756-763 

 

 

Selected Abstracts:

Augostini R, Merliss A, Jagielski D, Bourn DW, Abraham WT, Ponikowski P. Comparison of Right versus Left Phrenic Nerve Stimulation in Patients

Implanted with the remed?® System, Poster Presentation Heart Rhythm Society 2014

 

Abraham WT, Ponikowski P, Bourn DW, Germany R. Improvement in Sympathetic Activation Seen when Treating  CSA Using the remed?® System, Oral Presentation Heart and Brain 2014

 

Abraham WT,  Oldenburg O, Ponikowski P, Schwartz A, Bart B, Czarnecka D, Michalkiewicz D, Hasan A, Bourn DW. Phrenic Nerve Stimulation Improves Acute Circulatory Delay in Patients with Heart Failure and Central Sleep Apnea, Journal of Cardiac Failure.,2012;18:S14-15

 

Bourn DW, Trayanova NA, Gray RA. Virtual Electrode-Induced Propagated Graded Responses and Arrhythmogenesis  Heart Rhythm J.,2006;3:P5-9

 

Maleckar MM, Bourn DW, Rodriguez B, Trayanova NA. Mechanistic Insight into the Increase in the Upper Limit of Vulnerability to Electric Shocks Following Rapid Pacing. Heart Rhythm J.,2005;2:S219

 

Bourn DW, Trayanova NA, Gray RA. Isoelectric Window as a Function of Coupling Interval, PACE, 26:1044, 2003.

 

Bourn DW, Trayanova NA, Gray RA. Shock-Induced Arrhythmogenesis and the Isoelectric Window, PACE 25(partII):604, 2002.

 

Intellectual Property


Patent Applications:

  • 20090054947       Electrode Configurations for Directional Leads
  • 20090054941       Stimulation Field Management

 

Issued Patents:

  • 8295943 – Implantable Medical Lead with Biased Electrode; Issued 10-23-2012
  • 8326418 – Evaluating Therapeutic Stimulation Electrode Configurations Based on Physiological Responses; Issued 12-04-2012